The Substance won 6 awards (of the 7 categories it was nominated for) at the 59th Annual James Loutzenhiser Awards presented by the Kansas City Film Critics Circle (KCFCC) including Best Film, Best Science Fiction/fantasy/horror, Best Director for Coralie Fargeat, Best Actress for Demi Moore in a tie with Mikey Madison – Anora, and Best Supporting Actress for Margaret Qualley.

David Dastmalchian, who grew up in the Kansas City metropolitan area, won the award for Best Actor, for his portrayal in Late Night With the Devil, and Kieran Culkin won Best Supporting Actor for A Real Pain.

Other top awards went to Flow for Best Foreign Language Film, Will & Harper won Best Documentary and I Saw the TV Glow won Best LGBTQ Film.

Full List of the Kansas City Film Critics Circle 59th James Loutzenhiser Awards Winners and Runner-ups

BEST FILM

Winner: THE SUBSTANCE

Runner-Up: DUNE: PART II

ROBERT ALTMAN AWARD FOR BEST DIRECTOR

Winner: Coralie Fargeat – THE SUBSTANCE

Runner-Up: Sean Baker – ANORA

BEST ACTOR

Winner: David Dastmalchian – LATE NIGHT WITH THE DEVIL

Runner-Up: Ralph Fiennes – CONCLAVE

BEST ACTRESS

Winner (TIE): Mikey Madison – ANORA

Winner (TIE): Demi Moore – THE SUBSTANCE

BEST SUPPORTING ACTOR

Winner: Kieran Culkin – A REAL PAIN

Runner Up: Yura Borisov – ANORA

BEST SUPPORTING ACTRESS

Winner: Margaret Qualley – THE SUBSTANCE

Runner-Up: Danielle Deadwyler – THE PIANO LESSON

BEST ORIGINAL SCREENPLAY

Winner: THE SUBSTANCE

Runner-Up: ANORA

BEST ADAPTED SCREENPLAY

Winner: CONCLAVE

Runner-Up: NICKEL BOYS

BEST CINEMATOGRAPHY

Winner: THE BRUTALIST

Runner-Up: CIVIL WAR

BEST ORIGINAL SCORE

Winner: CHALLENGERS

Runner-Up: CONCLAVE

BEST ANIMATED FEATURE

Winner: THE WILD ROBOT

Runner-Up: FLOW

BEST FOREIGN LANGUAGE FILM

Winner: FLOW

Runner-Up: EMILIA PÉREZ

BEST DOCUMENTARY

Winner: WILL & HARPER

Runner-Up: SEEKING MAVIS BEACON

VINCE KOEHLER AWARD FOR BEST SCIENCE FICTION/FANTASY/HORROR

Winner: THE SUBSTANCE

Runner-Up: DUNE: PART TWO

TOM POE AWARD FOR BEST LGBTQ FILM

Winner: I SAW THE TV GLOW

Runner-Up: EMILIA PÉREZ

BUSTER KEATON AWARD FOR THE BEST STUNT ENSEMBLE FILM

Winner: THE FALL GUY

Runner-Up (TIE): FURIOSA: A MAD MAX SAGA/ DEADPOOL & WOLVERINE